IFNA 抗体
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北京 101111
Quick Overview for IFNA 抗体 (ABIN121866)
抗原
See all IFNA 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity chromatography on protein G
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免疫原
- Recombinant chicken Interferon alpha
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应用备注
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ELISA. Western Blot: This antibody cross reacts with IFN beta in western blots but does not show any cross reactivity with IFN gamma, this antibdoy detects a band of approximately 19 kDa. Functional Assays. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- IFNA (Interferon alpha (IFNA))
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别名
- Interferon alpha (IFN Alpha)
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背景
- The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.Synonyms: B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon
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途径
- JAK/STAT Signaling, TLR signaling, Hepatitis C, Inflammasome
抗原
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