TLR7 抗体 (AA 451-500)
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Quick Overview for TLR7 抗体 (AA 451-500) (ABIN121174)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 451-500
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特异性
- The antibody recognizes human TLR7. Other species not tested.
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纯化方法
- Protein-G affinity chromatography
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免疫原
- Recombinant human TLR7 (451-500 aa) purified from E. coli
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亚型
- IgG1
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应用备注
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ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution is 1:1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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别名
- TLR7
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背景
- TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.Synonyms: Toll-like receptor 7
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基因ID
- 51284
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UniProt
- Q9NYK1
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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