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TLR7 抗体 (AA 451-500)

This anti-TLR7 antibody is a 小鼠 单克隆 antibody detecting TLR7 in WB 和 EIA. Suitable for 人.
产品编号 ABIN121174
发货至: 中国

Quick Overview for TLR7 抗体 (AA 451-500) (ABIN121174)

抗原

See all TLR7 抗体
TLR7 (Toll-Like Receptor 7 (TLR7))

适用

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宿主

  • 93
  • 19
小鼠

克隆类型

  • 81
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  • 1
单克隆

标记

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This TLR7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

4F4
  • 抗原表位

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    AA 451-500

    特异性

    The antibody recognizes human TLR7. Other species not tested.

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant human TLR7 (451-500 aa) purified from E. coli

    亚型

    IgG1
  • 应用备注

    ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution is 1:1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    TLR7 (Toll-Like Receptor 7 (TLR7))

    别名

    TLR7

    背景

    TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7,8 genes are located on the sex chromosome X. hTLR7 may play an important role in detecting and combating viral infections.Synonyms: Toll-like receptor 7

    基因ID

    51284

    UniProt

    Q9NYK1

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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