MME 抗体
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北京 101111
Quick Overview for MME 抗体 (ABIN120746)
抗原
See all MME 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody LT10 reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.
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纯化方法
- Precipitation methods and ion exchange chromatography
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)
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亚型
- IgG1
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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
MME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibodyMME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7D4B1 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibodyMME 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibodyMME 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MME-1870 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibodyMME 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibodyMME 适用: 人 WB, IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal MME-1892 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 FITC
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 3G6B11 unconjugated
anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibodyMME 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6G12E12 unconjugated
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应用备注
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Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 4-8 °C for one month or at -20 °C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- CD10 / Neprilysin
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物质类
- Chemical
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背景
- CD10 (neutral endopeptidase NEP, common acute lymphocytic leukemia antigen CALLA, membrane metallo-endopeptidase MME, enkefalinase) is a 100- kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11
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基因ID
- 4311
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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