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CSK 抗体 (AA 330-450)

Name: CSK 抗体 (AA 330-450)
SKU: ABIN120744
Availability: OutOfStock

This anti-CSK antibody is a 小鼠单克隆 antibody detecting CSK in WB, IF 和 IP. Suitable for 人和小鼠.

产品编号 ABIN120744

发货至: 中国

Quick Overview for CSK 抗体 (AA 330-450) (ABIN120744)

抗原

See all CSK 抗体

CSK (C-Src tyrosine Kinase (CSK))

适用

人, 小鼠

宿主

小鼠

克隆类型

单克隆

标记

This CSK antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

CSK-04

Discover our top product CSK Primary Antibody

抗原表位
18

16

8

8

7

7

6

5

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 330-450

特异性

The antibody CSK-04 reacts with Csk (C-terminal Src kinase), a 50 kDa non-receptor protein tyrosine kinase expressed in cytosol.

纯化方法

Protein A affinity chromatography

纯度

> 95 % (by SDS-PAGE)

免疫原

Bacterially expressed recombinant fragment of human Csk corresponding to aa 330-450

亚型

IgG1
anti-C-Src tyrosine Kinase (CSK) (AA 1-100) antibody
CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated

anti-C-Src tyrosine Kinase (CSK) (C-Term) antibody
Verified CSK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 243-438) antibody
CSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibody
CSK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 67-101), (N-Term) antibody
CSK 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50568 unconjugated

anti-C-Src tyrosine Kinase (CSK) (Ser280) antibody
CSK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 330-450) antibody
CSK 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal CSK-04 unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibody
CSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Immunoprecipitation. Western Blotting (1:250-1:300. Weak non-specific band of cca 60 kDa is detected in human cell lines in lower antibody dilutions). Immunochemistry (Positive control: HeLa human cervix carcinoma cell line).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

1.0 mg/mL

缓冲液

Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

有效期

12 months
抗原

CSK (C-Src tyrosine Kinase (CSK))

别名

CSK

背景

C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase which resembles Src-family kinases, but unlike them lacks the conserved autophosphorylation site, the regulatory C-terminal tyrosine as well as myristylation and palmitylation. Csk negatively regulates Src-family kinases by phosphorylation of their C-terminal regulatory tyrosine. Disruption of the csk gene causes constitutive activation of Src-family kinases, and overexpression of Csk usually counteracts their signaling. The Csk-mediated regulation of those Src-family kinases that are localized in lipid rafts is enabled by a ubiquitously expressed transmembrane adaptor PAG (also known as Cbp, Csk-binding protein), which recruits Csk.Synonyms: C-SRC kinase, Protein-tyrosine kinase CYL, Tyrosine-protein kinase CSK

基因ID

1445

UniProt

P41240

途径

TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events