HLA-E 抗体
Our Local Distributor
北京 101111
Quick Overview for HLA-E 抗体 (ABIN120711)
抗原
See all HLA-E 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
-
纯化方法
- Protein-A affinity chromatography
-
纯度
- > 95 % pure (by SDS-PAGE)
-
免疫原
- Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide
-
亚型
- IgG1
-
-
-
-
应用备注
-
Flow Cytometry. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
-
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
-
-
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
-
背景
- HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on many types of the human cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.2, HLAE, MHC class I antigen E, alpha chain E
-
基因ID
- 3133
-
UniProt
- P13747
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
-