Endoglin 抗体
-
- 抗原 See all Endoglin (ENG) 抗体
- Endoglin (ENG)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Endoglin antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
- 交叉反应 (详细)
- Species reactivity (tested):Human
- 纯化方法
- Protein-A affinity chromatography
- 纯度
- > 95 % pure (by SDS-PAGE)
- 免疫原
- Recombinant Vaccinia Virus containing human CD105 cDNA
- 克隆位点
- MEM-226
- 亚型
- IgG2a
- Top Product
- Discover our top product ENG Primary Antibody
-
-
- 应用备注
-
Fow Cytometry. Immunoprecipitation. Western blotting (non-reducing conditions only).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - 有效期
- 12 months
-
- 抗原
- Endoglin (ENG)
- 别名
- CD105 / Endoglin (ENG 产品)
- 背景
- CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbR-2 as a receptor for TGFb-1 and TGFb-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFb-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.Synonyms: END, ENG, HHT1, ORW, ORW1
- UniProt
- P17813
-