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Endoglin 抗体

This anti-Endoglin antibody is a 小鼠 单克隆 antibody detecting Endoglin in WB, FACS 和 IP. Suitable for 人.
产品编号 ABIN120662
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Endoglin 抗体 (ABIN120662)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

MEM-226
  • 交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein-A affinity chromatography

    纯度

    > 95 % pure (by SDS-PAGE)

    免疫原

    Recombinant Vaccinia Virus containing human CD105 cDNA

    亚型

    IgG2a
  • 应用备注

    Fow Cytometry. Immunoprecipitation. Western blotting (non-reducing conditions only).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    Endoglin (ENG)

    别名

    CD105 / Endoglin

    背景

    CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbR-2 as a receptor for TGFb-1 and TGFb-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFb-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.Synonyms: END, ENG, HHT1, ORW, ORW1

    UniProt

    P17813
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