SIT1 抗体 (PE)
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北京 101111
Quick Overview for SIT1 抗体 (PE) (ABIN120659)
抗原
See all SIT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs.
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产品特性
- Synonyms: Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembraneadapter protein, Suppression-inducing transmembrane adapter 1
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免疫原
- Bacterially produced recombinant intracellular fragment of human SIT
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亚型
- IgG1
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anti-Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) antibody
SIT1 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal SIT-01 unconjugated
anti-Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) antibody (PE)SIT1 适用: 人 ICFC 宿主: 小鼠 Monoclonal SIT-01 PE
anti-Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1) (AA 161-189), (C-Term) antibodySIT1 适用: 人 WB 宿主: 兔 Polyclonal RB35945 unconjugated
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应用备注
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Suitable for Flow cytometry (1/50, intracellular staining). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch. -
有效期
- 12 months
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- SIT1 (Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))
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别名
- SIT1 / SIT
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背景
- SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.Synonyms: SHP2-interacting transmembrane adapter protein, Signaling threshold-regulating transmembrane adapter 1, Suppression-inducing transmembrane adapter 1
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基因ID
- 27240
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UniProt
- Q9Y3P8
抗原
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