CD41, CD61 抗体
Quick Overview for CD41, CD61 抗体 (ABIN120593)
抗原
See all CD41, CD61 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity Chromatography on Protein A .
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免疫原
- Bovine trombocytes
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亚型
- IgG2
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应用备注
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Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Frozen Sections. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM Sodium Azide as preservative, approx. pH 7.4.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- CD41, CD61 (CD41,CD61)
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背景
- CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIba (heavy chain, 120 kDa) and GPIIbb (light chain, 23 kDa). CD61 non-covalently associates with CD41. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes, the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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UniProt
- P08514
抗原
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