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CD15 抗体

FUT4 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-158 unconjugated
产品编号 ABIN120563
发货至: 中国
  • 抗原 See all CD15 (FUT4) 抗体
    CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))
    适用
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    宿主
    • 81
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    小鼠
    克隆类型
    • 93
    • 53
    • 1
    单克隆
    标记
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    This CD15 antibody is un-conjugated
    应用范围
    • 111
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    纯化方法
    Precipitation methods and ion exchange chromatography
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Human granulocytes
    克隆位点
    MEM-158
    亚型
    IgM
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    Discover our top product FUT4 Primary Antibody
  • 应用备注
    Flow Cytometry. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))
    别名
    CD15 (FUT4 产品)
    背景
    CD15 (Lewis X, Le(x), stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.Synonyms: Lacto-N-Fucopentaose III, Lewis X, SSEA1, Stage-Specific Embryonic Antigen, X-Hapten
    UniProt
    P22083
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