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CD15 抗体 (Biotin)

FUT4 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-158 Biotin
产品编号 ABIN120561
发货至: 中国
  • 抗原 See all CD15 (FUT4) 抗体
    CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))
    适用
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    宿主
    • 81
    • 66
    小鼠
    克隆类型
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    单克隆
    标记
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    This CD15 antibody is conjugated to Biotin
    应用范围
    • 111
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    Flow Cytometry (FACS)
    纯化方法
    Purified
    免疫原
    Human granulocytes
    克隆位点
    MEM-158
    亚型
    IgM
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  • 应用备注
    Suitable for Flow cytometry (1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4 with 15 mM sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 4-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))
    别名
    CD15 (FUT4 产品)
    背景
    CD15 (Lewis X, Le(x), stage specific embryonic antigen-1, SSEA-1) is a trisacharide (3-determinant3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.Synonyms: Lacto-N-Fucopentaose III, Lewis X, SSEA1, Stage-Specific Embryonic Antigen, X-Hapten
    UniProt
    P22083
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