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ICAM1 抗体 (FITC)

ICAM1 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 1A29 FITC
产品编号 ABIN120497
发货至: 中国
  • 抗原 See all ICAM1 抗体
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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    大鼠
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    小鼠
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    标记
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    This ICAM1 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes the CD54 cell surface antigen, also known as intercellular adhesion molecule-1 (ICAM-1). Recent studies suggest that cross-linking of ICAM-1 using clone 1A29 induces calcium signalling. Functionally 1A29 inhibits homotypic aggregation of PHA blasts. We recommend SM286LE for this use.
    交叉反应 (详细)
    Species reactivity (tested):Rat.
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Rat Ax cells (a rat HEV derived cell line). Remarks: Spleen cells from immunised BALB/c mice were fused with cells from the PAI mouse myeloma cell line.
    克隆位点
    1A29
    亚型
    IgG1
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • 应用备注
    Flow cytometry (Use 10 μL neat antibody to label 10^6 cells in 100 μL). Recent studies suggest that cross-linking of ICAM-1 using clone 1A29 induces calcium signalling (see Ref.3). Functionally 1A29 inhibits homotypic aggregation of PHA blasts. We recommend the use of ABIN182014 for this purpose.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL IgG
    缓冲液
    PBS, pH 7.2, containing 1 % BSA as stabiliser and 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    CD54 / ICAM1 (ICAM1 产品)
    别名
    BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
    物质类
    Viral Protein
    背景
    CD54 cell surface antigen, also known as the intercellular adhesion molecule-1 (ICAM-1), is a 90 kD adhesion molecule belonging to the immunoglobulin superfamily. This is a cell surface ligand of the lymphocyte integrin, LFA-1 and is known to play an important role in various cell-cell interactions in the immune system.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
    基因ID
    25464
    NCBI登录号
    NP_037099
    UniProt
    Q00238
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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