MCAM 抗体 (N-Term)
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Quick Overview for MCAM 抗体 (N-Term) (ABIN119671)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-5, N-Term
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特异性
- This antibody recognizes the 118 kDa cell surface glycoprotein CD146, also known as MUC18, Mel-CAM and S-endo. CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells. CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumor progression.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Recombinant human MUC18 (D1-D5) Fc protein. Spleen cells from immunised mice were fused with cells of the mouse Sp2/0 Ag.14 myeloma cell line.
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亚型
- IgG1
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anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 84-189) antibody
MCAM 适用: 人 IHC, FACS, WB, ELISA 宿主: 小鼠 Monoclonal 6C3E6 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 447-646) antibodyMCAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 50-646) antibodyMCAM 适用: 人 FACS, WB, IF, ELISA 宿主: 小鼠 Monoclonal 4D10C7 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人 IHC, FACS, WB, IF, ELISA 宿主: 兔 Monoclonal 8A10 unconjugated Recombinant Antibody
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyKD Validated MCAM 适用: 人 FACS, WB 宿主: 兔 Monoclonal 23GB2705 unconjugated Recombinant Antibody
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) antibodyMCAM 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 226-374) antibodyMCAM 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MCAM-3046 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 201-300) antibodyMCAM 适用: 人, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 106 cells. Immunohistochemistry on frozen sections. Recommended positive control tissue: Melanoma. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, None, None
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody at -20 °C only.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- CD146
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背景
- CD146 is a member of the immunoglobulin superfamily, expressed by all endothelial cells and by melanoma cells. CD146 appears to act as an adhesion molecule. Expression in melanoma may be linked to tumour progression.Synonyms: A32, CD146, Cell surface glycoprotein P1H12, MCAM, MUC18, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen
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基因ID
- 4162
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NCBI登录号
- NP_006491
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UniProt
- P43121
抗原
-
