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DAXX 抗体 (C-Term)

DAXX 适用: 人, 小鼠 WB, IF 宿主: 小鼠 Monoclonal DAXX-01 unconjugated
产品编号 ABIN119584
发货至: 中国
  • 抗原 See all DAXX 抗体
    DAXX (Death-Domain Associated Protein (DAXX))
    抗原表位
    • 22
    • 18
    • 16
    • 16
    • 15
    • 15
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 558-740, C-Term
    适用
    • 170
    • 57
    • 43
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 154
    • 18
    小鼠
    克隆类型
    • 143
    • 29
    单克隆
    标记
    • 71
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 1
    This DAXX antibody is un-conjugated
    应用范围
    • 155
    • 78
    • 78
    • 46
    • 36
    • 32
    • 23
    • 21
    • 20
    • 13
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    The antibody reacts with Daxx, a death domain containing protein mainly expressed in fetal and adult tissue.
    纯化方法
    Affinity Chromatography on Protein-A.
    免疫原
    Recombinant C-terminal part (aa 558-740) of Human Daxx
    克隆位点
    DAXX-01
    亚型
    IgG1
    Top Product
    Discover our top product DAXX Primary Antibody
  • 应用备注
    Western Blot. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DAXX (Death-Domain Associated Protein (DAXX))
    别名
    DAXX (DAXX 产品)
    别名
    BING2 antibody, DAP6 antibody, EAP1 antibody, LOC100226911 antibody, daxx antibody, si:dz179b20.7 antibody, wu:fd15c03 antibody, death domain associated protein antibody, Fas death domain-associated protein antibody, 28S ribosomal protein S29, mitochondrial antibody, death-domain associated protein antibody, death-associated protein 6 L homeolog antibody, DAXX antibody, Daxx antibody, LOC100226911 antibody, daxx.L antibody, daxx antibody
    背景
    Daxx is an apoptosis-modulating death-domain associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein
    基因ID
    1616
    NCBI登录号
    NP_001135441
    UniProt
    Q9UER7
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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