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DAXX 抗体 (C-Term)

This 小鼠 单克隆 antibody specifically detects DAXX in WB 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN119584
发货至: 中国
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Quick Overview for DAXX 抗体 (C-Term) (ABIN119584)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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人, 小鼠

宿主

  • 154
  • 16
小鼠

克隆类型

  • 132
  • 38
单克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

DAXX-01
  • 抗原表位

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    AA 558-740, C-Term

    特异性

    The antibody reacts with Daxx, a death domain containing protein mainly expressed in fetal and adult tissue.

    纯化方法

    Affinity Chromatography on Protein-A.

    免疫原

    Recombinant C-terminal part (aa 558-740) of Human Daxx

    亚型

    IgG1
  • 应用备注

    Western Blot. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    Daxx is an apoptosis-modulating death-domain associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein

    基因ID

    1616

    NCBI登录号

    NP_001135441

    UniProt

    Q9UER7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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