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CD46 抗体

CD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
产品编号 ABIN119581
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
    • 113
    • 34
    • 20
    • 10
    • 10
    • 3
    人, Cow
    宿主
    • 79
    • 52
    • 2
    小鼠
    克隆类型
    • 69
    • 64
    单克隆
    标记
    • 52
    • 14
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This CD46 antibody is un-conjugated
    应用范围
    • 81
    • 75
    • 38
    • 35
    • 27
    • 17
    • 14
    • 14
    • 13
    • 9
    • 6
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    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    交叉反应 (详细)
    Species reactivity (tested):Human, Bovine.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    HPB-ALL human T cell line
    克隆位点
    MEM-258
    亚型
    IgG1
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注
    Western blotting (non-reducing conditions). Immunoprecipitation. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Tris buffered saline (TBS) pH ~8.0, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the original vial at 2-8 °C. Freeze stock solution or aliquots thereof at -20 °C.
  • 抗原
    CD46
    别名
    CD46 / MCP (CD46 产品)
    背景
    CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    基因ID
    9606
    UniProt
    P15529
    途径
    Regulation of Actin Filament Polymerization
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