CD46 抗体
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北京 101111
Quick Overview for CD46 抗体 (ABIN119581)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 (详细)
- Species reactivity (tested):Human, Bovine.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- HPB-ALL human T cell line
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亚型
- IgG1
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应用备注
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Western blotting (non-reducing conditions). Immunoprecipitation. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Tris buffered saline (TBS) pH ~8.0, 15 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the original vial at 2-8 °C. Freeze stock solution or aliquots thereof at -20 °C.
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- CD46
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别名
- CD46 / MCP
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背景
- CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
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基因ID
- 9606
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UniProt
- P15529
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途径
- Regulation of Actin Filament Polymerization
抗原
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