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GZMB 抗体

GZMB 适用: 人, 猴, Chimpanzee FACS, IF, IP, IHC (fro), EIA 宿主: 小鼠 Monoclonal GB11 unconjugated
产品编号 ABIN119565
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    适用
    • 119
    • 49
    • 24
    • 9
    • 4
    • 2
    • 1
    人, 猴, Chimpanzee
    宿主
    • 80
    • 42
    • 1
    小鼠
    克隆类型
    • 76
    • 47
    单克隆
    标记
    • 77
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is un-conjugated
    应用范围
    • 71
    • 42
    • 37
    • 36
    • 19
    • 17
    • 17
    • 14
    • 13
    • 10
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a Capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (SM1805B) as detection reagent.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    Purified human Granzyme B. Remarks: Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
    克隆位点
    GB11
    亚型
    IgG1
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections. Flow cytometry: 1/10 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood, Membrane permeabilisation is required for this application. Immunoprecipitation. ELISA: 2 μg/mL - 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Tris buffered saline containing 0.09 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GZMB (Granzyme B (GZMB))
    Abstract
    GZMB 产品
    别名
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    背景
    Ganzyme B is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
    基因ID
    3002
    NCBI登录号
    NP_004122
    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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