GZMB 抗体
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北京 101111
Quick Overview for GZMB 抗体 (ABIN119565)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a Capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (SM1805B) as detection reagent.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- Purified human Granzyme B. Remarks: Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
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亚型
- IgG1
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anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) antibodyGZMB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-4C1 unconjugated
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应用备注
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Immunohistochemistry on frozen sections. Flow cytometry: 1/10 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood, Membrane permeabilisation is required for this application. Immunoprecipitation. ELISA: 2 μg/mL - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Tris buffered saline containing 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GZMB (Granzyme B (GZMB))
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背景
- Ganzyme B is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
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基因ID
- 3002
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NCBI登录号
- NP_004122
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UniProt
- P10144
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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