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GZMB 抗体 (Biotin)

This anti-GZMB antibody is a 小鼠 单克隆 antibody detecting GZMB in EIA. Suitable for 人.
产品编号 ABIN119564
发货至: 中国

Quick Overview for GZMB 抗体 (Biotin) (ABIN119564)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

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  • 51
  • 26
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宿主

  • 94
  • 92
  • 2
小鼠

克隆类型

  • 101
  • 87
单克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This GZMB antibody is conjugated to Biotin

应用范围

  • 92
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Enzyme Immunoassay (EIA)

克隆位点

GB10
  • 特异性

    This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (SM1806P) as capture reagent.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    Purified human Granzyme B. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.

    亚型

    IgG1
  • 应用备注

    ELISA: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 0.001 % Thiomersal

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GZMB (Granzyme B (GZMB))

    背景

    Ganzyme B which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E

    基因ID

    3002

    NCBI登录号

    NP_004122

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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