GZMA 抗体
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北京 101111
Quick Overview for GZMA 抗体 (ABIN119562)
抗原
See all GZMA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises Granzyme A.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- Recombinant Granzyme A. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
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亚型
- IgG1
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应用备注
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Immunohistochemistry on paraffin sections: 1/50 - 1/200, This product requires antigen retrieval using heat treatment prior to staining of paraffin sections, Sodium citrate buffer pH 6.0 is recommended for this purpose. Western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- TRIS buffered saline containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
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别名
- Granzyme A (GZMA)
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背景
- Ganzyma A is a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.Synonyms: CTL tryptase, CTLA3, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, H factor, HFSP, Hanukkah factor
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基因ID
- 3001
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NCBI登录号
- NP_006135
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UniProt
- P12544
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途径
- Apoptosis
抗原
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