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CD80 抗体 (FITC)

This anti-CD80 antibody is a 小鼠 单克隆 antibody detecting CD80 in FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN119433
发货至: 中国

Quick Overview for CD80 抗体 (FITC) (ABIN119433)

抗原

See all CD80 抗体
CD80

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD80 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-233
  • 特异性

    The antibody reacts with CD80.

    免疫原

    CD80 fusion protein

    亚型

    IgG1
  • 应用备注

    Flow cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Ryu, Lee, Hong, Shin, Lim, Park, Shim, Nam, Choi, Kim, Han: "Activation of fractalkine/CX3CR1 by vascular endothelial cells induces angiogenesis through VEGF-A/KDR and reverses hindlimb ischaemia." in: Cardiovascular research, Vol. 78, Issue 2, pp. 333-40, (2008) (PubMed).

  • 抗原

    CD80

    别名

    CD80

    背景

    CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 Molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80

    基因ID

    941

    NCBI登录号

    NP_005182

    UniProt

    P33681

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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