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CD80 抗体

This anti-CD80 antibody is a 小鼠 单克隆 antibody detecting CD80 in FACS, WB 和 IP. Suitable for 人.
产品编号 ABIN119430
发货至: 中国

Quick Overview for CD80 抗体 (ABIN119430)

抗原

See all CD80 抗体
CD80

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD80 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

MEM-233
  • 特异性

    This antibody recognises the CD80 cell surface antigen, also known as B7-1.

    纯化方法

    Affinity chromatography on Protein A

    亚型

    IgG1
  • 应用备注

    Flow Cytometry. Immunoprecipitation. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS

    储存液

    Azide free

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    CD80

    别名

    CD80

    背景

    CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines. CD80 is expressed by activated B cells, and is important in B cell - T cell interactions, being a ligand of CD28 and CD152 (CTLA-4).Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80

    基因ID

    941

    NCBI登录号

    NP_005182

    UniProt

    P33681

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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