KIT 抗体
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- 抗原 See all KIT 抗体
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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适用
- 人, 猴, Cow
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KIT antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognizes the CD117 cell surface antigen. This antibody is Non-Neutralising.
- 纯化方法
- Affinity Chromatography
- 免疫原
- MOLM-1 megakaryocyte cell line.
- 克隆位点
- 104D2
- 亚型
- IgG1
- Top Product
- Discover our top product KIT Primary Antibody
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anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 350-440) antibody
KIT 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 321-520) antibodyKIT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 343-527) antibodyKIT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr721) antibodyKIT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (pTyr703) antibodyKIT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (Internal Region) antibodyVerified KIT 适用: 人 WB, ELISA, FACS, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 546-976) antibodyKIT 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 25-295) antibodyKIT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 50-190) antibodyKIT 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL1667 unconjugated
anti-Mast/stem Cell Growth Factor Receptor (KIT) (AA 50-190) antibodyKIT 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL1657 unconjugated
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- 应用备注
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Flow Cytometry: 1/2 - 1/20, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- 别名
- CD117 / C-Kit (KIT 产品)
- 别名
- C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
- 背景
- C-kit, also known as stem cell factor receptor, steel factor receptor or CD117 is classified as a type III receptor tyrosine kinase (RTK) belonging to the platelet-derived growth factor receptor subfamily. Binding of stem cell factor (SCF), known as c-kit ligand to c-kit initiate autophosphorylation of the receptor, subsequently leading to promotes a signal transduction cascade through Ras-Raf-MAP kinase cascade, phosphatidylinositol-3-kinase, src family kinases, and STATs. The role of c-kit includes maturation of hematopoietic and primordial germ cells precursors and melanocytes during embryonic development. In acute myeloid leukemia (AML), c-kit has been proposed to play a functional role, and becomes target molecule for drug development.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR
- 基因ID
- 3815
- NCBI登录号
- NP_000213
- UniProt
- P10721
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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