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CDK6 抗体

CDK6 适用: 人 WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal DCS-83-1 unconjugated
产品编号 ABIN119189
发货至: 中国
  • 抗原 See all CDK6 抗体
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CDK6 antibody is un-conjugated
    应用范围
    • 76
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises Cyclin Dependent Kinase 6 (Cdk6), a 40 kDa protein which plays an important role in the progression of G1 to S.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Purified
    免疫原
    Recombinant CDK6 protein.
    克隆位点
    DCS-83-1
    亚型
    IgG1
    Top Product
    Discover our top product CDK6 Primary Antibody
  • 应用备注
    Western Blot. Immunoprecipitation. Immunohistochemistry on frozen sections. Recommended positive control tissue: U-2-OS sarcoma cell line.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.08 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    别名
    CDK6 (CDK6 产品)
    别名
    CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
    背景
    Cdk6 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of Cdk6 first appears in mid-G1 phase, and is controlled by regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE
    基因ID
    1021
    NCBI登录号
    NP_001138778
    UniProt
    Q00534
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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