HLA B7 抗体
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Quick Overview for HLA B7 抗体 (ABIN118934)
抗原
See all HLA B7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the HLA-B7 antigen and does not cross-react with HLA-B27 or other related antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of diseases such as ankylosing spondylitis and anterior uveitis.
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Papain solubilized HLA-B7 antigen.
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亚型
- IgG1
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anti-HLA Class I B7 Alpha (HLA B7) antibody (PE)
HLA B7 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal BB7-1 PE
anti-HLA Class I B7 Alpha (HLA B7) antibodyHLA B7 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal BB7-1 unconjugated
anti-HLA Class I B7 Alpha (HLA B7) antibody (PE)HLA B7 适用: 人, Cynomolgus FACS 宿主: 小鼠 Monoclonal BB7-1 PE
anti-HLA Class I B7 Alpha (HLA B7) antibody (FITC)HLA B7 适用: 人, Cynomolgus FACS 宿主: 小鼠 Monoclonal BB7-1 FITC
anti-HLA Class I B7 Alpha (HLA B7) antibodyHLA B7 适用: 人, Cynomolgus FACS 宿主: 小鼠 Monoclonal BB7-1 unconjugated
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应用备注
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Flow Cytometry: 1/50, Use 10 μL of the suggested working dilution to label 1 x 10^6 cells or 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HLA B7 (HLA Class I B7 Alpha (HLA B7))
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背景
- HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). This antibody can be used for HLA typing.Synonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7
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基因ID
- 3106
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NCBI登录号
- NP_005505
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UniProt
- P01889
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途径
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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