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FGF2 抗体

FGF2 适用: 人 WB, IHC (p), EIA, IHC (fro) 宿主: 小鼠 Monoclonal MC-GF1 unconjugated
产品编号 ABIN118917
发货至: 中国
  • 抗原 See all FGF2 抗体
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FGF2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises basic fibroblast growth factor (bFGF). The antibody binds strongly to bFGF attached to proteoglycans, but is competitively displaced by heparin. Not suitable for detecting bFGF bound to cell surface receptors.
    纯化方法
    Protein G chromatography
    免疫原
    Recombinant human bFGF
    克隆位点
    MC-GF1
    亚型
    IgG2a
    Top Product
    Discover our top product FGF2 Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections. ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    别名
    FGF Basic / FGF2 (FGF2 产品)
    别名
    BFGF antibody, FGF-2 antibody, FGFB antibody, HBGF-2 antibody, Fgf-2 antibody, Fgfb antibody, bFGF antibody, fibroblast growth factor 2 antibody, fibroblast growth factor 2 (basic) antibody, FGF2 antibody, Fgf2 antibody, fgf2 antibody
    背景
    FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.Synonyms: BFGF, FGFB, Fibroblast growth factor 2 (basic), HBGF-2, HBGF2, Heparin-binding growth factor 2
    基因ID
    2247
    NCBI登录号
    NP_001997
    UniProt
    P09038
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
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