Endoglin 抗体 (PE)
Quick Overview for Endoglin 抗体 (PE) (ABIN118833)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the human CD105 cell surface antigen, a glycoprotein homodimer of 95 kDa subunits.
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Partially purified cell membrane antigens from fresh leukaemia cells
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亚型
- IgG1
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应用备注
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Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1.0 mL distilled water.
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缓冲液
- PBS, pH 7.4, containing 0.09 % sodium azide as preservative and 1 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- This product is photosensitive and should be protected from light
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储存条件
- 4 °C
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储存方法
- Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
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- Endoglin (ENG)
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别名
- CD105 / Endoglin
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背景
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.Synonyms: END, ENG, HHT1, ORW, ORW1
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基因ID
- 9606
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UniProt
- P17813
抗原
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