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Endoglin 抗体 (FITC)

ENG 适用: 人, 马 FACS 宿主: 小鼠 Monoclonal SN6 FITC
产品编号 ABIN118831
发货至: 中国
  • 抗原 See all Endoglin (ENG) 抗体
    Endoglin (ENG)
    适用
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    人, 马
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Endoglin antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    SM1177F recognizes the CD105 cell surface antigen.
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Partially purified cell membrane antigens from fresh leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/NS1/1-Ag4-1 myeloma cell line
    克隆位点
    SN6
    亚型
    IgG1
    Top Product
    Discover our top product ENG Primary Antibody
  • 应用备注
    Flow cytometry (use 10 μL of neat antibody to label 10^6 cells in 100 μL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as a preservative and 1 % BSA as a stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Endoglin (ENG)
    别名
    CD105 / Endoglin (ENG 产品)
    别名
    ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody
    背景
    CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. CD105 is a glycoprotein homodimer of 95 kD subunits. CD105 is expressed by endothelial cells, activated monocytes and some leukaemia cells.Synonyms: END, ENG, HHT1, ORW, ORW1
    基因ID
    9606
    UniProt
    P17813
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