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CD55 抗体 (PE)

There is 1 publication for this product available. The 小鼠 单克隆 anti-CD55 antibody is suitable to detect CD55 in samples from 人. It has been validated for FACS.
产品编号 ABIN118739
发货至: 中国
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Quick Overview for CD55 抗体 (PE) (ABIN118739)

抗原

See all CD55 抗体
CD55 (Complement Decay-Accelerating Factor (CD55))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD55 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

67
  • 纯化方法

    Affinity chromatography on Protein G.

    免疫原

    K562 cells

    亚型

    IgG1
  • 应用备注

    Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with distilled water.

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
  • Wenzel, Zabojszcza, Carl, Taubert, Lass, Harris, Ho, Schulz, Hummel, Hubner, Osterziel, Spuler: "Increased susceptibility to complement attack due to down-regulation of decay-accelerating factor/CD55 in dysferlin-deficient muscular dystrophy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 9, pp. 6219-25, (2005) (PubMed).

  • 抗原

    CD55 (Complement Decay-Accelerating Factor (CD55))

    别名

    CD55 / DAF

    背景

    CD55 is the complement regulatory protein, decay accelerating factor (DAF). It is a 70kD glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens. DAF has a wide distribution on cells in non-haemopoietic tissues, particularly epithelium and is specifically found at the foetal-maternal interface in placenta. Soluble forms of DAF are found, for example, in plasma, saliva and urine. The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin.Synonyms: Complement decay-accelerating factor

    基因ID

    9606

    UniProt

    P08174

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity
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