(1 reference)-
- 抗原 See all CD55 抗体
- CD55 (Complement Decay-Accelerating Factor (CD55))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD55 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 纯化方法
- Affinity Chromatography on Protein G
- 免疫原
- K562 cells
- 克隆位点
- 67
- 亚型
- IgG1
- Top Product
- Discover our top product CD55 Primary Antibody
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anti-Complement Decay-Accelerating Factor (CD55) (AA 35-134) antibody
CD55 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-285) antibodyCD55 适用: 人 WB, ELISA, IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 40-300) antibodyCD55 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 51-79) antibodyCD55 适用: 人 WB, FACS, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-134) antibodyCD55 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (Center) antibodyCD55 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 254-372) antibodyCD55 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) (AA 35-126) antibodyCD55 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Decay-Accelerating Factor (CD55) antibodyCD55 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 1A5 unconjugated Recombinant Antibody
anti-Complement Decay-Accelerating Factor (CD55) antibodyCD55 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal F4-29D9 unconjugated
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- 应用备注
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Flow Cytometry: use 10 μL of 1/10-1/25 diluted antibody to label 10^6 cells in 100 μL. We do not recommend the use of this reagent to stain erythrocytes. Immunohistochemistry on Frozen Sections (1/100-1/1000). Recommended positive control: Human Tonsil. (Successful use in Immunohistochemistry on Paraffin embedded sections (1/50-1/100)using heat treatment for antigen retrieval) was reported by some researchers. As thisdetection method has not been verified by antibodies-online, the application was deletedfrom the database. This does not necessarily exclude the use in such procedure.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Increased susceptibility to complement attack due to down-regulation of decay-accelerating factor/CD55 in dysferlin-deficient muscular dystrophy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 9, pp. 6219-25, (2005) (PubMed).
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: "Increased susceptibility to complement attack due to down-regulation of decay-accelerating factor/CD55 in dysferlin-deficient muscular dystrophy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 9, pp. 6219-25, (2005) (PubMed).
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- 抗原
- CD55 (Complement Decay-Accelerating Factor (CD55))
- 别名
- CD55 / DAF (CD55 产品)
- 别名
- CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
- 背景
- Avoidance by host tissues of attack by autologous complement proteins is dependent in part on the activities of membrane regulatory factors. One molecule involved in this control is a 70 kD glycoprotein termed decay-accelerating factor (DAF), or CD55. Interruption by CD55 of the complement sequence at an early step in activation effectively halts progression of the cascade and prevents consequent cell injury. In man, CD55 is expressed on the plasma membrane of all cell types that are in intimate contact with plasma complement proteins. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. CD55 also acts as the receptor for echovirus 7 and related viruses(echoviruses 13, 21, 29 and 33). It is attached to the membrane by a GPI-anchor.Synonyms: Complement decay-accelerating factor
- 基因ID
- 9606
- UniProt
- P08174
- 途径
- Complement System, Regulation of Leukocyte Mediated Immunity
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