CD35 抗体
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北京 101111
Quick Overview for CD35 抗体 (ABIN118606)
抗原
See all CD35 (CR1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Human acute monocytic leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
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亚型
- IgG1
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应用备注
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Flow Cytometry: 1/50 - 1/100, use 10 μL of the suggested working dilution to label 1x10^6 cells or 100 μL whole blood. Immunohistochemistry on frozen and paraffin sections. Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, None, None
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储存液
- Without preservative
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
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别名
- CD35 / C3BR
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背景
- CD35 is a membrane glycoprotein found on peripheral blood cells, glomerular podocytes, and follicular dendritic cells. The protein is a receptor for complement components C3b and C4b and regulates the activity of the complement cascade. Variation in this protein is the basis of the Knops blood group system. The two most common alleles, F and S, differ by 8 exons and are thought to be the result of an unequal crossover event. A secreted form of the protein present in plasma has been described, but its full length nature has not been determined.Synonyms: C3b/C4b receptor, CR1, Complement receptor type 1
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基因ID
- 9606
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UniProt
- P17927
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
抗原
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