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CD7 抗体 (Biotin)

This 小鼠 单克隆 antibody specifically detects CD7 in FACS 和 IHC (fro). It exhibits reactivity toward 人.
产品编号 ABIN118543
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for CD7 抗体 (Biotin) (ABIN118543)

抗原

See all CD7 抗体
CD7

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD7 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

LT7
  • 特异性

    This antibody is a single chain cell surface glycoprotein of 40 kDa, expressed by T cells, NK cells and thymocytes. CD7 is also expressed by tumour cells in some cases of acute myeloid leukaemia.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    Normal human peripheral blood lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the X63.653 mouse myeloma cell line.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % Bovine Serum Albumin as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD7

    别名

    CD7

    背景

    CD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin superfamily. CD7 is expressed by the majority of thymocytes and mature T cells, NK cells and pre-B cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The function of CD7 is not yet known although cross-linking of CD7 with antibodies induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin. The CD7 Molecule has been reported to be the receptor for the IgM-Fc portion (FcR mu) on the surface of T cells.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

    基因ID

    924

    NCBI登录号

    NP_006128

    UniProt

    P09564

    途径

    Cell-Cell Junction Organization
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