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CD5 抗体 (PE)

This anti-CD5 antibody is a 小鼠 单克隆 antibody detecting CD5 in FACS. Suitable for 人.
产品编号 ABIN118497
发货至: 中国

Quick Overview for CD5 抗体 (PE) (ABIN118497)

抗原

See all CD5 抗体
CD5

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD5 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MF7-14-5
  • 特异性

    This antibody recognises the CD5 cell surface glycoprotein, a 67 kDa antigen expressed by T lymphocytes and by a subset of B lymphocytes.

    纯化方法

    Affinity chromatography on Protein G

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: Use 10 μL of Neat antibody to label 10^6 cells or 100 μL whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with distilled water.

    缓冲液

    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
  • 抗原

    CD5

    别名

    CD5

    背景

    CD5 is a 55 kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.Synonyms: CD5, LEU1, Lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5

    基因ID

    921

    NCBI登录号

    NP_055022

    UniProt

    P06127
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