ICAM1 抗体
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北京 101111
Quick Overview for ICAM1 抗体 (ABIN118125)
抗原
See all ICAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with ICAM-1 (CD54) present on T-cells, B-cells, monocytes and endothelial cells.
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纯化方法
- Affinity chromatography on Protein G
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过滤
- Sterile
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亚型
- IgG
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应用备注
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Flow cytometry: 50 μg/mL, Use 5 μL of the suggested working dilution to label 10^6 cells in 105 μL. Immunohistochemistry on frozen sections. ELISA. Functional assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Sterile filtered PBS
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
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- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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别名
- CD54 / ICAM1
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背景
- ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
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基因ID
- 15894
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NCBI登录号
- NP_034623
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UniProt
- P13597
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
抗原
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