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ICAM1 抗体

ICAM1 适用: 小鼠 FACS, IHC (fro), Func, EIA 宿主: 仓鼠 Monoclonal 3E2B unconjugated
产品编号 ABIN118125
发货至: 中国
  • 抗原 See all ICAM1 抗体
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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    仓鼠
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    单克隆
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    This ICAM1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts with ICAM-1 (CD54) present on T-cells, B-cells, monocytes and endothelial cells.
    纯化方法
    Affinity chromatography on Protein G
    过滤
    Sterile
    克隆位点
    3E2B
    亚型
    IgG
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • 应用备注
    Flow cytometry: 50 μg/mL, Use 5 μL of the suggested working dilution to label 10^6 cells in 105 μL. Immunohistochemistry on frozen sections. ELISA. Functional assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Sterile filtered PBS
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    CD54 / ICAM1 (ICAM1 产品)
    物质类
    Viral Protein
    背景
    ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
    基因ID
    15894
    NCBI登录号
    NP_034623
    UniProt
    P13597
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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