RNF2 抗体 (AA 189-201)
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北京 101111
Quick Overview for RNF2 抗体 (AA 189-201) (ABIN117940)
抗原
See all RNF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 189-201
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序列
- 1 msqavqtngt qplsktwels lyelqrtpqe aitdgleivv sprslhselm cpicldmlkn 61 tmttkeclhr fcadciital rsgnkecptc rkklvskrsl rpdpnfdali skiypsrdey 121 eahqervlar inkhnnqqal shsieeglki qamnrlqrgk kqqiengsga edngdsshcs 181 nasthsnqea gpsnkrtkts ddsgleldnn naamaidpvm dgaseielvf rphptlmekd 241 dsaqtryikt sgnatvdhls kylavrlale elrskgesnq mnldtasekq ytiyiatasg 301 qftvlngsfs lelvsekywk vnkpmelyya ptkehk
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特异性
- This antibody detects RING1B.
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交叉反应 (详细)
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Species reactivity (expected):Zebrafish.
Species reactivity (tested):Human, Chimpanzee, Orangutan, Mouse, Rrat, Dog, Bovine, Frog and Chicken. -
纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic peptide corresponding aa 189-201 of Human RING1B protein
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应用备注
- ELISA: 1/5,000-1/25,000. Western blot: 1/500-1/2,000. Expect a band approximately 38 kDa in size corresponding toRING1B by in the appropriate cell lysate or extract. Immunofluorescence.
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限制
- 仅限研究用
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浓度
- 1.2 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 as buffer and 0.01 % (w/v) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8 °C. DO NOT FREEZE!
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- RNF2 (Ring Finger Protein 2 (RNF2))
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别名
- RNF2
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背景
- RING1B (also known as BAP1, DING, Polycomb-M33 interacting protein Ring1B, Ring finger protein 1b, Ring finger protein 2 and RNF2) is one of the PcG proteins. The polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), a ubiquitin-conjugating enzyme that possesses ubiquitin ligase activity.Synonyms: BAP-1, BAP1, DING, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, HIPI3, Protein DinG, RING finger protein 2, RING1B
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基因ID
- 6045
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NCBI登录号
- NP_009143
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UniProt
- Q99496
抗原
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