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GSK3 alpha 抗体 (AA 16-25)

Name: GSK3 alpha 抗体 (AA 16-25)
SKU: ABIN117907
Availability: OutOfStock

This 兔多克隆 antibody specifically detects GSK3 alpha in WB 和 EIA. It exhibits reactivity toward 人.

产品编号 ABIN117907

发货至: 中国

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Quick Overview for GSK3 alpha 抗体 (AA 16-25) (ABIN117907)

抗原

See all GSK3 alpha (GSK3a) 抗体

GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

适用

人

宿主

兔

克隆类型

多克隆

标记

This GSK3 alpha antibody is un-conjugated

应用范围

Western Blotting (WB), Enzyme Immunoassay (EIA)

Discover our top product GSK3a Primary Antibody

抗原表位
32

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6

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3

2

2

2

2

2

2

2

2

1

1

1

1

1

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1

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1

1

1

1

1

1
AA 16-25

序列

Peptide sequence: R-A-R-T-S-S-F-A-E-P-C

特异性

This is an affinity purified antibody produced by Immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

纯化方法

Immunoaffinity chromatography.

免疫原

This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the aa 16-25 of human GSK3 alpha.
anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (pSer21) antibody
GSK3a 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (pTyr216), (pTyr279) antibody
GSK3a 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibody
KO Validated GSK3a 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (pSer21) antibody
GSK3a 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 122-406) antibody
GSK3a 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 76-105), (N-Term) antibody
GSK3a 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3817-3818 unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 409-483) antibody
GSK3a 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibody
GSK3a 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 9D5G1 unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibody
GSK3a 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 6G2F1 unconjugated

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibody
KD Validated GSK3a 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB855 unconjugated Recombinant Antibody

应用备注

This affinity purified antibody has been tested for use in ELISA against the immunizingpeptide. Reactivity in other immunoassays is unknown. Recommended dilutions: This product has been assayed by ELISA against 0.1 μg of theimmunizing peptide. A 1: 4,000 to 1: 16,000 dilution of the antibody is recommended forthis assay. This antibody reacts equally with both the phosphorylated andnon-phosphorylated forms of the peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.00 mg/mL (by UV absorbance at 280 nm)

缓冲液

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
抗原

GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

别名

GSK3 alpha

背景

Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily, GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97 % sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.Synonyms: Factor A, GSK-3 alpha, GSK3A, Glycogen synthase kinase-3 alpha

基因ID

2931

NCBI登录号

NP_063937

UniProt

P49840

途径

PI3K-Akt Signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect