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CD4 抗体

CD4 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal RPA-T4 unconjugated
产品编号 ABIN1177369
发货至: 中国
  • 抗原 See all CD4 抗体
    CD4
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD4 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Functional Studies (Func)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    克隆位点
    RPA-T4
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD4 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • 抗原
    CD4
    别名
    CD4 (CD4 产品)
    背景
    The RPA-T4 clone reacts with CD4, a 59 kDa single-chain transmembrane glycoprotein [receptor for human immunodeficiency virus (HIV)] present on T-helper/inducer cell populations. This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. CD4 is also present in low density on peripheral blood monocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation. This antibody is capable of blocking mixed-lymphocyte reaction (MLR).
    途径
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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