(1 reference)-
- 抗原 See all CD226 抗体
- CD226
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD226 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func)
- 品牌
- BD Pharmingen™
- 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- 克隆位点
- DX11
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD226 Primary Antibody
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anti-CD226 (CD226) (AA 19-254) antibody
CD226 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (Tyr570) antibodyCD226 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 19-254) antibodyCD226 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8D11D5 unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal DX11 unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 19-247) antibodyCD226 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM95 unconjugated
anti-CD226 (CD226) (AA 287-336), (pSer329) antibodyCD226 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (C-Term) antibodyCD226 适用: 人, 小鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (pSer329) antibodyCD226 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes." in: Immunity, Vol. 4, Issue 6, pp. 573-81, (1996) (PubMed).
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: "DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes." in: Immunity, Vol. 4, Issue 6, pp. 573-81, (1996) (PubMed).
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- 抗原
- CD226
- 别名
- CD226 (CD226 产品)
- 背景
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Reacts with DNAX accessory molecule-1 (DNAM-1), a 65 kDa transmembrane glycoprotein consisting of 318 amino acid residues including two Ig-like domains. DNAM-1 is expressed on the majority of T cells, NK cells, monocytes, and a subset of B cells, but not on granulocytes or erythrocytes. It is also present on a subset of thymocytes coexpressing high density surface CD3. DNAM-1 is not present on normal fibroblast cell lines or tumor cell lines of epithelial or neuronal origins. DNAM-1 is a tyrosinephosphorylated, signal-transducing molecule which participates in primary adhesion during cytotoxic T lymphocyte (CTL)-mediated cytotoxicity. DX11 inhibits T- and NKcell-mediated cytotoxicity against a variety of tumor cell targets, and blocks cytokine production by alloantigen-specific T cells.
Synonyms: DNAM-1 - 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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