Interferon gamma 抗体
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北京 101111
Quick Overview for Interferon gamma 抗体 (ABIN1177289)
抗原
See all Interferon gamma (IFNG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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Neutralization Activity: 50% Neutralization (ND50) at 1-150 ng/mL
>95% Neutralization at 60-500 ng/ml -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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免疫原
- Recombinant Mouse IFN-gamma
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亚型
- IgG1 kappa
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anti-Interferon gamma (IFNG) (AA 75-155) antibody
IFNG 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) (AA 81-166) antibodyIFNG 适用: 人 WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) (AA 23-156) antibodyIFNG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) antibody (Biotin)IFNG 适用: 人, Non-Human Primate WB, ELISA, FACS, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal 4S-B3 Biotin
anti-Interferon gamma (IFNG) antibodyIFNG 适用: 人 IHC, FACS, IF 宿主: 小鼠 Monoclonal IFNG-466 unconjugated
anti-Interferon gamma (IFNG) antibodyIFNG 适用: 人, Non-Human Primate WB, ELISA, FACS, IP, ICC, IHC (p), RIA 宿主: 小鼠 Monoclonal 4S-B3 unconjugated
anti-Interferon gamma (IFNG) antibodyMicroarray verified IFNG 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB393378 unconjugated
anti-Interferon gamma (IFNG) antibodyIFNG 适用: 人 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal F2E4 unconjugated
anti-Interferon gamma (IFNG) (AA 24-166) antibodyIFNG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) (AA 24-167) antibody (APC)IFNG 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC
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应用备注
- In vitro neutralization: The NA/LE format of the H22 antibody (Cat. No. 557530) is useful for the in vitro neutralization of mouse IFN-gamma bioactivity. Assay Type: EMC viral resistance assay Using 1.0 ng/ml recombinant mouse IFN-gamma (Cat. No. 554587) and preincubation of antibody and ligand = 60 minutes Indicator cell: L929 at 2 x10^5 cells/ml
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies." in: Infection and immunity, Vol. 60, Issue 1, pp. 84-9, (1992) (PubMed).
: "A T cell-independent mechanism of macrophage activation by interferon-gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 139, Issue 4, pp. 1104-7, (1987) (PubMed).
: "Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 21, pp. 7404-8, (1985) (PubMed).
: "Rapid, quantitative, semiautomated assay for virus-induced and immune human interferons." in: Journal of clinical microbiology, Vol. 12, Issue 3, pp. 433-8, (1981) (PubMed).
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- Interferon gamma (IFNG)
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别名
- IFN-gamma
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背景
- The H22 antibody reacts with mouse interferon-gamma (IFN-gamma , but not mouse IFN-alpha , IFN-beta , IL-6, or human IFN-gamma. The H22 antibody was reported to inhibit the in vitro anti-viral, the class II MHC antigen-inducing and the macrophage-activating factor (MAF) activities of mouse IFN-gamma. Moreover, the IFN-gamma neutralizing capacity of has been reported in several in vivo model systems. The specific binding of I[125] -labeled recombinant mouse IFN-gamma to IFN-gamma receptor-positive cells is blocked by H22. Although the H22 antibody is reported to react with rat IFN-gamma , its reactivity with IFN-gamma from other species has not been tested.
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途径
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
抗原
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