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WIPF1 抗体 (pSer488) (PE)

This anti-WIPF1 antibody is a 小鼠 单克隆 antibody detecting WIPF1 in ICS. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1177221
发货至: 中国

Quick Overview for WIPF1 抗体 (pSer488) (PE) (ABIN1177221)

抗原

See all WIPF1 抗体
WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

适用

  • 19
  • 8
  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 19
小鼠

克隆类型

  • 19
单克隆

标记

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WIPF1 antibody is conjugated to PE

应用范围

  • 12
  • 7
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Intracellular Staining (ICS)

克隆位点

K32-824
  • 抗原表位

    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer488

    品牌

    BD Phosflow™

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Phosphorylated Human WIP Peptide

    亚型

    IgG1 kappa
  • 样本量

    20 μL

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
  • Aspenström: "The verprolin family of proteins: regulators of cell morphogenesis and endocytosis." in: FEBS letters, Vol. 579, Issue 24, pp. 5253-9, (2005) (PubMed).

  • 抗原

    WIPF1 (WAS/WASL Interacting Protein Family, Member 1 (WIPF1))

    别名

    WIP

    背景

    Wiskott-Adrich syndrome protein (WASP)-Interacting Protein (WIP) is a member of the verprolin family of proteins that regulate cytoskeletal organization in a wide variety of cellular activities, including endocytosis, cellular adhesion and migration, mast cell degranulation, and lymphocyte activation. The 503-amino acid WIP protein contains binding sites for actin (globular and filamentous) and other proteins that are involved in the regulation of actin polymerization, such as WASP, N-WASP, profilin, cortactin, Hck, and NCK. As its functions imply, WIP is localized in actin-rich cell structures. The K32-824 monoclonal antibody recognizes the phosphorylated serine 488 (pS488) of human WIP. The orthologous phosphorylation sites in mouse and rat WIP are S478 and S472, respectively.

    途径

    RTK signaling
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