P-Selectin 抗体
(7 references)Quick Overview for P-Selectin 抗体 (ABIN1177016)
抗原
See all P-Selectin (SELP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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免疫原
- P-selectin-IgG1 Fusion
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亚型
- IgG1 lambda
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anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 701-768) antibody
SELP 适用: 人, 大鼠, 小鼠, Pig WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 198-432) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 58-158) antibodySELP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal AK4 unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 30-200) antibodySELP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 58-195) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC, Func 宿主: 小鼠 Monoclonal AK4 unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibody (Biotin)SELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal AK4 Biotin
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (N-Term) antibodySELP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 198-432) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C9 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "P-, E-, and L-selectin mediate migration of activated CD8+ T lymphocytes into inflamed skin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 8, pp. 4307-13, (2002) (PubMed).
: "Selective accumulation of type 1 effector cells expressing P-selectin ligand and/or alpha(4)beta(7)-integrin at the lesions of autoimmune gastritis." in: International immunology, Vol. 14, Issue 2, pp. 167-75, (2002) (PubMed).
: "CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 2, pp. 963-70, (1998) (PubMed).
: "P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflammed tissues." in: Nature, Vol. 385, Issue 6611, pp. 81-3, (1997) (PubMed).
: "Mouse P-selectin glycoprotein ligand-1: molecular cloning, chromosomal localization, and expression of a functional P-selectin receptor." in: Blood, Vol. 87, Issue 10, pp. 4176-86, (1996) (PubMed).
: "Only simultaneous blocking of the L- and P-selectin completely inhibits neutrophil migration into mouse peritoneum." in: European journal of immunology, Vol. 24, Issue 12, pp. 3019-24, (1995) (PubMed).
: "Sequential contribution of L- and P-selectin to leukocyte rolling in vivo." in: The Journal of experimental medicine, Vol. 181, Issue 2, pp. 669-75, (1995) (PubMed).
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: "P-, E-, and L-selectin mediate migration of activated CD8+ T lymphocytes into inflamed skin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 8, pp. 4307-13, (2002) (PubMed).
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- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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别名
- CD62P (P-selectin)
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背景
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The RB40.34 antibody reacts with mouse P-selectin (CD62P), a 140 kDa protein which is expressed on activated platelets, activated endothelial cells, and megakaryocytes. P-selectin mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells, mediates leukocyte rolling, and is involved in the migration of leukocytes into inflamed tissues. CD24 and CD162 (PSGL-1) are ligands of CD62P. mAb RB40.34 can block mouse P-selectin binding to its ligands in vitro and in vivo.
Synonyms: P-selectin
抗原
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