Interferon gamma 抗体
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北京 101111
Quick Overview for Interferon gamma 抗体 (ABIN1176984)
抗原
See all Interferon gamma (IFNG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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Neutralization Activity: This antibody has been reported to be useful for the neutralization of mouse IFN-gamma anti-viral activity. Neutralization activity may be measured with a encphalomyocarditis viral (EMCV) resistance assay using 1 ng/mL recombinant mouse IFN-gamma (Cat. No. 554587) with L929 indicator cells.
50% Neutralization (ND50) at 1 - 20 ng/mL
95% Neutralization at 15 - 333 ng/mL -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
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免疫原
- Mouse IFN-gamma Recombinant Protein
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亚型
- IgG1 kappa
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anti-Interferon gamma (IFNG) (AA 75-155) antibody
IFNG 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) (AA 81-166) antibodyIFNG 适用: 人 WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) (AA 23-156) antibodyIFNG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) antibody (Biotin)IFNG 适用: 人, Non-Human Primate WB, ELISA, FACS, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal 4S-B3 Biotin
anti-Interferon gamma (IFNG) antibodyIFNG 适用: 人 IHC, FACS, IF 宿主: 小鼠 Monoclonal IFNG-466 unconjugated
anti-Interferon gamma (IFNG) antibodyIFNG 适用: 人, Non-Human Primate WB, ELISA, FACS, IP, ICC, IHC (p), RIA 宿主: 小鼠 Monoclonal 4S-B3 unconjugated
anti-Interferon gamma (IFNG) antibodyMicroarray verified IFNG 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB393378 unconjugated
anti-Interferon gamma (IFNG) antibodyIFNG 适用: 人 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal F2E4 unconjugated
anti-Interferon gamma (IFNG) (AA 24-166) antibodyIFNG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma (IFNG) (AA 24-167) antibody (APC)IFNG 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2μm sterile filtered.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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: "Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." in: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).
: "In vivo cytokine production in murine listeriosis. Evidence for immunoregulation by gamma delta+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 1, pp. 232-7, (1996) (PubMed).
: "Differential production of interferon-gamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by gamma delta T cells in vivo." in: Nature, Vol. 373, Issue 6511, pp. 255-7, (1995) (PubMed).
: "Induction of cytokines in mice with parainfluenza pneumonia." in: Journal of virology, Vol. 69, Issue 2, pp. 1288-91, (1995) (PubMed).
: "Enumeration of IFN-gamma producing lymphocytes by flow cytometry and correlation with quantitative measurement of IFN-gamma." in: Journal of immunological methods, Vol. 173, Issue 2, pp. 219-28, (1994) (PubMed).
: "Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 3, pp. 1246-53, (1994) (PubMed).
: "A simple, sensitive, dual mAb based ELISA for murine gamma interferon determination: comparison with two common bioassays." in: Journal of immunoassay, Vol. 14, Issue 3, pp. 129-48, (1993) (PubMed).
: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).
: "Rapid, quantitative, semiautomated assay for virus-induced and immune human interferons." in: Journal of clinical microbiology, Vol. 12, Issue 3, pp. 433-8, (1981) (PubMed).
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- Interferon gamma (IFNG)
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别名
- IFN-gamma
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背景
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The XMG1.2 monoclonal antibody specifically binds to mouse interferon-gamma (IFN-gamma) protein. IFN-gamma is a pleiotropic cytokine, of approximately 15-17 kDa, involved in the regulation of inflammatory and immune responses. It plays an important role in activation, growth, and differentiation of T and B lymphocytes, macrophages, NK cells and other non-hematopoietic cell types. IFN-gamma production is associated with the Th1 cell differentiation. The purified form of this antibody has been reported to be a neutralizing antibody.
Synonyms: IFN-gamma, IFN-g, IFN-gamma, Interferon gamma, Type II Interferon -
途径
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
抗原
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