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CD11b 抗体

This anti-CD11b antibody is a 小鼠 单克隆 antibody detecting CD11b in FACS 和 Func. Suitable for 人.
产品编号 ABIN1176910
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD11b 抗体 (ABIN1176910)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

ICRF44
  • 纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

    免疫原

    Human monocytes

    亚型

    IgG1 kappa
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    CD11b/Mac-1

    背景

    The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin beta2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
    Synonyms: Mac-1alpha, integrin alphaM subunit, CR3 alpha chain

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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