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CD11b 抗体

ITGAM 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal ICRF44 unconjugated
产品编号 ABIN1176910
发货至: 中国
  • 抗原 See all CD11b (ITGAM) 抗体
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD11b antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Functional Studies (Func)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    免疫原
    Human monocytes
    克隆位点
    ICRF44
    亚型
    IgG1 kappa
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  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    CD11b/Mac-1 (ITGAM 产品)
    背景
    The ICRF44 monoclonal antibody reacts with CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin beta2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
    Synonyms: Mac-1alpha, integrin alphaM subunit, CR3 alpha chain
    途径
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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