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CD20 抗体 (PE)

Cited in 1 publication. This anti-CD20 antibody is a 小鼠 单克隆 antibody detecting CD20 in ICS. Suitable for 人.
产品编号 ABIN1176880
发货至: 中国
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Room 801-803
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Quick Overview for CD20 抗体 (PE) (ABIN1176880)

抗原

See all CD20 (MS4A1) 抗体
CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD20 antibody is conjugated to PE

应用范围

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Intracellular Staining (ICS)

克隆位点

H1
  • 品牌

    BD Phosflow™

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Human B lymphoma cell line

    亚型

    IgG2a kappa
  • 说明

    BALB/c

    样本量

    5 μL

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Cragg, Walshe, Ivanov, Glennie: "The biology of CD20 and its potential as a target for mAb therapy." in: Current directions in autoimmunity, Vol. 8, pp. 140-74, (2004) (PubMed).

  • 抗原

    CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

    别名

    CD20

    背景

    The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.
    Synonyms: MS4A1, membrane-spanning 4-domains subfamily A member 1, B1, Bp35, LEU-16
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