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ACE2 抗体

This anti-ACE2 antibody is a 小鼠 单克隆 antibody detecting ACE2 in WB, ELISA 和 FACS. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1169449
发货至: 中国

Quick Overview for ACE2 抗体 (ABIN1169449)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

适用

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宿主

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小鼠

克隆类型

  • 127
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单克隆

标记

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This ACE2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

AC18F
  • 特异性

    Recognizes human ACE2.

    交叉反应

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human ACE2.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • Chaouat, Achdout, Kol, Berhani, Roi, Vitner, Melamed, Politi, Zahavy, Brizic, Lenac Rovis, Alfi, Wolf, Jonjic, Israely, Mandelboim: "SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection." in: PLoS pathogens, Vol. 17, Issue 12, pp. e1010175, (2022) (PubMed).

    Chaouat, Brizic, Kucan Brlic, Atari, Kliker, Alfi, Mandelboim, Wolf, Tafish, Kol, Jonjic, Mandelboim: "Anti-human ACE2 antibody neutralizes and inhibits virus production of SARS-CoV-2 variants of concern." in: iScience, Vol. 25, Issue 9, pp. 104935, (2022) (PubMed).

    Buchrieser, Dufloo, Hubert, Monel, Planas, Rajah, Planchais, Porrot, Guivel-Benhassine, Van der Werf, Casartelli, Mouquet, Bruel, Schwartz: "Syncytia formation by SARS-CoV-2-infected cells." in: The EMBO journal, pp. e106267, (2020) (PubMed).

    Zulli, Rai, Buxton, Burrell, Hare: "Co-localization of angiotensin-converting enzyme 2-, octomer-4- and CD34-positive cells in rabbit atherosclerotic plaques." in: Experimental physiology, Vol. 93, Issue 5, pp. 564-9, (2008) (PubMed).

  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    别名

    ACE2

    背景

    ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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