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Granulin 抗体

GRN 适用: 人 WB, IHC, ELISA 宿主: 豚鼠 Polyclonal unconjugated
产品编号 ABIN1169391
发货至: 中国
  • 抗原 See all Granulin (GRN) 抗体
    Granulin (GRN)
    适用
    • 50
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 9
    • 5
    • 2
    豚鼠
    克隆类型
    • 47
    • 11
    多克隆
    标记
    • 34
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Granulin antibody is un-conjugated
    应用范围
    • 51
    • 18
    • 16
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    Recognizes human progranulin. Detects a band of ~90 kDa by Western blot.
    交叉反应
    交叉反应 (详细)
    Weakly cross-reacts with mouse progranulin. Cross-reacts with hGRN-C and hGRN-F.
    过滤
    0.2 μm filtered
    免疫原
    Recombinant human progranulin.
    Top Product
    Discover our top product GRN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    Granulin (GRN)
    别名
    Progranulin (GRN 产品)
    别名
    GRN antibody, grn antibody, wu:fb11g12 antibody, wu:fj18f05 antibody, MGC53354 antibody, DKFZp459H066 antibody, CLN11 antibody, GEP antibody, GP88 antibody, PCDGF antibody, PEPI antibody, PGRN antibody, epithelin antibody, acrogranin antibody, granulin precursor antibody, granulin a antibody, Granulins antibody, granulin L homeolog antibody, granulin antibody, GRN antibody, grna antibody, grn antibody, grn.L antibody, granulin antibody, ORF1 granulin antibody, Grn antibody
    物质类
    Viral Protein
    背景
    Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
    UniProt
    P28799
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