TRAIL 抗体
(4 references)Quick Overview for TRAIL 抗体 (ABIN1169389)
抗原
See all TRAIL (TNFSF10) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human TRAIL.
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交叉反应
- 人
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纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant human TRAIL.
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亚型
- IgG1
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 39-250) antibody
TNFSF10 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 185-281) antibodyTNFSF10 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 95-281) antibodyTNFSF10 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 95-281) antibody (PE)TNFSF10 适用: 人 FACS 宿主: 小鼠 Monoclonal 2E5 PE
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 115-287) antibodyTNFSF10 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 1-300) antibodyTNFSF10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 1-300) antibodyTNFSF10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 95-281) antibodyTNFSF10 适用: 人 FACS 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (Internal Region) antibodyTNFSF10 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 40-291) antibodyTNFSF10 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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: "Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence." in: Journal of cellular and molecular medicine, Vol. 14, Issue 9, pp. 2292-304, (2010) (PubMed).
: "Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors." in: Cell death and differentiation, Vol. 13, Issue 10, pp. 1740-51, (2006) (PubMed).
: "Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape." in: Gastroenterology, Vol. 128, Issue 7, pp. 1796-804, (2005) (PubMed).
: "TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 4, pp. 1814-21, (2003) (PubMed).
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: "Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence." in: Journal of cellular and molecular medicine, Vol. 14, Issue 9, pp. 2292-304, (2010) (PubMed).
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- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
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别名
- TRAIL
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背景
- TNF-related apoptosis-inducing ligand (TRAIL, Apo2L,CD253, TNFSF10) is a type II transmembrane protein of about 34 kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to five distinct receptors: TRAIL-R1 (DR4, Apo2, CD261, TNFRSF10A), TRAIL-R2 (DR5, KILLER, TRICK2A, TRICK2B, CD262, TNFRSF10B), TRAIL-R3 (DcR1, LIT, TRID, CD263, TNFRSF10C), TRAIL-R4 (DcR2, TRUNDD, CD264, TNFRSF10D), and osteoprotegerin (OPG, OCIF, TNFRSF11B). Trimerized TRAIL triggers apoptosis upon ligation of cell surface TRAIL-R1 and/or TRAIL-R2 by inducing the formation of the so-called multiprotein death-inducing signaling complex (DISC). .
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UniProt
- P50591
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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