Caspase 1 (p10) 抗体 (Biotin)
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北京 101111
Quick Overview for Caspase 1 (p10) 抗体 (Biotin) (ABIN1169387)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (Biotin)
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特异性
- Recognizes endogenous full-length and activated (p10 fragment) mouse caspase-1.
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产品特性
- Monoclonal Antibody. Recognizes endogenous full-length and activated (p10 fragment) mouse caspase-1. Isotype: Mouse IgG2a. Clone: Casper-2. Applications: WB. Liquid. In PBS containing 0.02 % sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
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纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant mouse caspase-1.
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亚型
- IgG2a
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anti-Caspase 1 (p10) (CASP-1 (p10)) (AA 320-404) antibody
CASP-1 (p10) 适用: 人, 小鼠, 大鼠, 小鸡 WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (p10) (CASP-1 (p10)) antibodyCASP-1 (p10) 适用: 小鼠 WB 宿主: 小鼠 Monoclonal Casper-2 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- Caspase 1 (p10) (CASP-1 (p10))
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别名
- Caspase-1 p10
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背景
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Alternate Names/Synonyms: Interleukin-1beta Convertase, IL-1BC, Interleukin-1beta-converting Enzyme, ICE
Product Description: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
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UniProt
- P29452
抗原
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