Caspase 1 (p10) 抗体
Cited in 6+ publications. This 小鼠 单克隆 anti-Caspase 1 (p10) antibody (Clone Casper-2) specifically detects Caspase 1 (p10) in WB. The antibody is reactive with 小鼠 samples.
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(6 references)
产品编号 ABIN1169386
发货至:
中国
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Quick Overview for Caspase 1 (p10) 抗体 (ABIN1169386)
抗原
Caspase 1 (p10) (CASP-1 (p10))
适用
小鼠
宿主
小鼠
克隆类型
单克隆
标记
This Caspase 1 (p10) antibody is un-conjugated
应用范围
Western Blotting (WB)
克隆位点
Casper-2
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特异性
- Recognizes endogenous full-length and activated (p10 fragment) mouse caspase-1.
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交叉反应
- 小鼠
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纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant mouse caspase-1.
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亚型
- IgG2a
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anti-Caspase 1 (p10) (CASP-1 (p10)) (AA 320-404) antibody
CASP-1 (p10) 适用: 人, 小鼠, 大鼠, 小鸡 WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 1 (p10) (CASP-1 (p10)) (C-Term) antibodyCASP-1 (p10) 适用: 人, 小鼠, 大鼠 WB, IC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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: "Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction." in: Frontiers in cell and developmental biology, Vol. 8, pp. 167, (2020) (PubMed).
: "Protective Role of Shiitake Mushroom-Derived Exosome-Like Nanoparticles in D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice." in: Nutrients, Vol. 12, Issue 2, (2020) (PubMed).
: "Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR." in: The Journal of experimental medicine, Vol. 216, Issue 12, pp. 2838-2853, (2020) (PubMed).
: "Repositioning of the β-Blocker Carvedilol as a Novel Autophagy Inducer That Inhibits the NLRP3 Inflammasome." in: Frontiers in immunology, Vol. 9, pp. 1920, (2018) (PubMed).
: "NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes." in: The Journal of experimental medicine, Vol. 214, Issue 5, pp. 1351-1370, (2017) (PubMed).
: "XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation." in: Cell reports, Vol. 7, Issue 6, pp. 1796-808, (2014) (PubMed).
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: "Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction." in: Frontiers in cell and developmental biology, Vol. 8, pp. 167, (2020) (PubMed).
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- Caspase 1 (p10) (CASP-1 (p10))
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别名
- Caspase-1 p10
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背景
- Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
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UniProt
- P29452
抗原
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