Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
Lot specific
缓冲液
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
储存液
Without preservative
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C.
有效期
6 months
抗原
FOXP3
(Forkhead Box P3 (FOXP3))
别名
FOXP3
背景
FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.