FOXP3 抗体
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北京 101111
Quick Overview for FOXP3 抗体 (ABIN1169337)
抗原
See all FOXP3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes mouse FOXP3. Detects a band of ~46-49 kDa by Western blot.
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交叉反应
- 小鼠
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant mouse FOXP3.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
有效期
- 6 months
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- FOXP3 (Forkhead Box P3 (FOXP3))
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别名
- FOXP3
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背景
- FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
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UniProt
- Q99JB6
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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